i(12p) in a malignant ovarian tumor

F Speleman; C De Potter; P Dal Cin; K Mangelschots; H Ingelaere; G Laureys; Y Benoit; J Leroy; H Van Den Berghe

doi:10.1016/0165-4608(90)90065-i

i(12p) in a malignant ovarian tumor

Cancer Genet Cytogenet. 1990 Mar;45(1):49-53. doi: 10.1016/0165-4608(90)90065-i.

Authors

F Speleman¹, C De Potter, P Dal Cin, K Mangelschots, H Ingelaere, G Laureys, Y Benoit, J Leroy, H Van Den Berghe

Affiliation

¹ Department of Medical Genetics, University Hospital Gent, Belgium.

PMID: 2302685
DOI: 10.1016/0165-4608(90)90065-i

Abstract

We have found one or more copies of i(12p) in an ovarian germ cell tumor, histologically a yolk sac tumor. This chromosome marker is characteristically associated with germ cell tumors in males. This report indicates that further investigation is necessary to establish the role of the i(12p) marker in the pathogenesis of germ cell tumors also in females.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Child, Preschool
Chromosome Aberrations*
Chromosome Banding
Chromosomes, Human, Pair 12*
Female
Genetic Markers
Humans
Karyotyping
Mesonephroma / genetics*
Mesonephroma / pathology
Ovarian Neoplasms / genetics*
Ovarian Neoplasms / pathology

Substances

Genetic Markers