Characterization of a verocytotoxin-producing enteroaggregative Escherichia coli serogroup O111:H21 strain associated with a household outbreak in Northern Ireland

Tim Dallman; Geoffrey P Smith; Brendan O'Brien; Marie A Chattaway; David Finlay; Kathie A Grant; Claire Jenkins

doi:10.1128/JCM.02047-12

Characterization of a verocytotoxin-producing enteroaggregative Escherichia coli serogroup O111:H21 strain associated with a household outbreak in Northern Ireland

J Clin Microbiol. 2012 Dec;50(12):4116-9. doi: 10.1128/JCM.02047-12. Epub 2012 Oct 3.

Authors

Tim Dallman¹, Geoffrey P Smith, Brendan O'Brien, Marie A Chattaway, David Finlay, Kathie A Grant, Claire Jenkins

Affiliation

¹ Laboratory of Gastrointestinal Pathogens, Health Protection Agency, London, United Kingdom.

Abstract

A strain of Escherichia coli O111:H21 recently isolated in the United Kingdom harbored the phage-encoded vtx2c gene and the aggregative adherence plasmid. Although exhibiting the same pathogenic profile as the E. coli O104:H4 strain linked to the outbreak in Germany, there were important differences in strain characteristics and in the epidemiological setting.

Publication types

Case Reports

MeSH terms

Animals
Child, Preschool
Cluster Analysis
Coliphages / genetics
Disease Outbreaks*
Escherichia coli / classification
Escherichia coli / genetics
Escherichia coli / isolation & purification*
Escherichia coli Infections / epidemiology*
Escherichia coli Infections / microbiology
Family Characteristics*
Family Health*
Female
Humans
Male
Molecular Epidemiology
Multilocus Sequence Typing
Northern Ireland / epidemiology
Plasmids
Prophages / genetics
Serotyping
Shiga Toxin 2 / genetics
Shiga-Toxigenic Escherichia coli / classification
Shiga-Toxigenic Escherichia coli / genetics
Shiga-Toxigenic Escherichia coli / isolation & purification*

Substances

Shiga Toxin 2