Abstract
In February 2011, a 78-year-old male patient was admitted to Clinical Hospital Center Zagreb with subdural haematoma. Klebsiella pneumoniae with reduced susceptibility to carbapenems was isolated. PCR revealed the presence of bla(KPC), bla(TEM), and bla(SHV) genes. Sequencing of bla(KPC) gene identified K. pneumoniae carbapenemase (KPC)-2 beta-lactamase. The strain belonged to ST37 clone by multilocus sequence typing. Infection control efforts limited the spread of KPC-producing clone of K. pneumoniae in our hospital so far. To our knowledge, this is the first report of a KPC-producing K. pneumoniae in Croatia.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism*
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Carbapenems / metabolism
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Carbapenems / pharmacology*
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Croatia
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Drug Resistance, Multiple, Bacterial*
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Fatal Outcome
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Hematoma, Subdural / surgery
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Humans
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Klebsiella Infections / drug therapy
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Klebsiella Infections / microbiology*
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Klebsiella pneumoniae / drug effects*
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Klebsiella pneumoniae / isolation & purification
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Klebsiella pneumoniae / metabolism*
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Male
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Meningitis, Bacterial / drug therapy
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Meningitis, Bacterial / microbiology
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Postoperative Complications / drug therapy
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Postoperative Complications / microbiology
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beta-Lactamases / genetics
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beta-Lactamases / metabolism*
Substances
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Bacterial Proteins
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Carbapenems
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beta-Lactamases
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beta-lactamase KPC-2, Klebsiella pneumoniae