Atrial electromechanical delay and diastolic dysfunction in primary Sjögren syndrome

Clin Invest Med. 2012 Oct 6;35(5):E303. doi: 10.25011/cim.v35i5.18703.

Abstract

Purpose: In this study we aimed to investigate myocardial function and atrial electromechanical properties by conventional and tissue doppler echocardiography in patients with primary Sjögren syndrome.

Methods: Forty patients with Sjögren syndrome (SS) and 25 age- and sex-matched healthy volunteers were enrolled in the study. Using transthoracic echocardiography, myocardial performance index and atrial electromechanical properties were measured.

Results: Basal characteristics were similar between two groups. Myocardial performance index values were disturbed in patients with Sjögren syndrome (0.41 vs. 0.32, p < 0.01). There was significant intraatrial (16.4±6.4, 5.0±4.5, p < 0.01) and interatrial (30.6±10.1, 15.4±5.9, p < 0.01) electromechanical delay in this patient group.

Conclusion: Myocardial function is disturbed and there is significant atrial electromechanical delay in patients with primary SS. This study is the first to show altered myocardial function and atrial electromechanical properties in primary SS.

MeSH terms

  • Atrial Fibrillation / complications
  • Atrial Fibrillation / physiopathology
  • Case-Control Studies
  • Diastole / physiology*
  • Echocardiography, Doppler
  • Female
  • Heart / physiopathology*
  • Heart Atria / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Sjogren's Syndrome / complications
  • Sjogren's Syndrome / physiopathology*
  • Stroke Volume / physiology