Cerebral venous thrombosis after lumbar puncture and intravenous high dose corticosteroids: a case report of a childhood multiple sclerosis

Brain Dev. 2013 Jun;35(6):602-5. doi: 10.1016/j.braindev.2012.09.001. Epub 2012 Oct 6.

Abstract

The association between cerebral venous thrombosis (CVT) and multiple sclerosis (MS) has already been reported in several adult patients with clinically definite MS, in a suspected relation to i.v. corticosteroids or previously performed lumbar puncture (LP). We are reporting a case, which is, to our knowledge, the first one concerning a child patient with a MS, who developed multiple CVT after LP and during high-dose i.v. corticosteroid. Our conclusions are that the sequence LP followed by high dose corticosteroids may be a contributory factor for the development of CVT when associated with other risk factors.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / adverse effects*
  • Brain / pathology
  • Female
  • Humans
  • Intracranial Thrombosis / etiology*
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Multiple Sclerosis / diagnostic imaging
  • Multiple Sclerosis / drug therapy*
  • Radiography
  • Spinal Cord / pathology
  • Spinal Puncture / adverse effects

Substances

  • Adrenal Cortex Hormones