Antibody persistence after Pandemic H1N1 2009 influenza vaccination among healthcare workers in Pune, India

Hum Vaccin Immunother. 2013 Jan;9(1):125-7. doi: 10.4161/hv.22421. Epub 2012 Oct 9.

Abstract

The healthcare workers having seroprotection at 3 weeks (n = 127) following Pandemic H1N1 2009 influenza vaccination were followed up for antibody persistence. Seroprotection at 12 mo (60.2%) was significantly lower as compared with 3 weeks (74.7%), 3 mo (77.8%) and 6 mo (75.4%). The vaccine provided seroprotection up to one year.

Keywords: Pandemic H1N1 2009; antibody persistence; healthcare workers; immune response; influenza vaccination; post-licensure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Viral / blood*
  • Female
  • Follow-Up Studies
  • Health Personnel*
  • Humans
  • India
  • Influenza A Virus, H1N1 Subtype / immunology*
  • Influenza Vaccines / administration & dosage
  • Influenza Vaccines / immunology*
  • Influenza, Human / immunology
  • Influenza, Human / prevention & control*
  • Influenza, Human / virology*
  • Male
  • Middle Aged
  • Time Factors
  • Young Adult

Substances

  • Antibodies, Viral
  • Influenza Vaccines