Measurement of somatosensory-evoked potential to evaluate function of the trigeminal nerve after rapid palatal expansion treatment in a rabbit model

Objective: The aim of this study was to evaluate whether high force or stress response occurs in rapid palatal expansion (RPE) on the skull base would affect the function of trigeminal nerve and its branches by measuring trigeminal somatosensory-evoked potential (TSEP).

Study design: Twenty-four male New Zealand white rabbits were selected when they were 12-13 weeks old with mean weight around 3.05 ± 0.33 kg. A modified acrylic-bonded RPE appliance was used as an expansion tool. Through a series of TSEP measurements performed before the expansion treatment (T0), on the third day of the expansion (T1), at the end of the expansion process (T2), and after 10 days of retention (T3), function of the trigeminal nerve was analyzed with statistical models, including the Kruskal-Wallis test and paired t tests.

Results: A stable short-latency response represented by a "W" waveform was consistently identified on the TSEP spectram analysis. Within-subject comparisons between the experimental group and control group did not show significant differences on TSEP of maxillary nerve and of mandibular nerve.

Conclusions: TSEP is a valuable technique for a comprehensive evaluation of the trigeminal system. Our study demonstrates that rapid palatal expansion is a safe orthopedic method regarding function of the trigeminal nerve during expansion and short-term retention period in young rabbits.