[Pain in patients with opiates dependence]

Presse Med. 2012 Dec;41(12 Pt 1):1221-5. doi: 10.1016/j.lpm.2012.07.030. Epub 2012 Oct 16.
[Article in French]

Abstract

We have to trust the patient. Pain is undertreated. Inadequate treatment has adverse consequences. Over and under treatment are both liabilities. Opioid-maintained patients do experience pain. These patients report higher pain scores. They experience both opioid tolerance and hyperalgesia. They are responsive to opioid analgesia. They need baseline opioids ("opioid debt"), mostly a well-stabilized OST. They require higher doses, more frequent dosing and longer opioid administration.

Publication types

  • English Abstract

MeSH terms

  • Analgesics, Opioid / administration & dosage*
  • Analgesics, Opioid / adverse effects
  • Analgesics, Opioid / therapeutic use
  • Drug Tolerance
  • Humans
  • Hyperalgesia / drug therapy*
  • Hyperalgesia / physiopathology
  • Opioid-Related Disorders / physiopathology*
  • Pain / drug therapy*
  • Pain / physiopathology

Substances

  • Analgesics, Opioid