Objectives: To examine acylcarnitine profiles in individuals with hypo- or hyperthyroidism, and determine whether any atypical acylcarnitine species identified would normalize with correction of thyroid status.
Design and methods: Serum acylcarnitine levels were measured in hypo- and hyperthyroid subjects before and after treatment with thyroxine or thionamide therapy respectively.
Results: No discernible differences were observed in the serum acylcarnitine profiles between hypo-, hyper- and euthyroid states.
Conclusions: Acylcarnitine profiles are relatively unremarkable in thyroid disease.
Copyright © 2012 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.