Complex evolution and epidemiology of Dobrava-Belgrade hantavirus: definition of genotypes and their characteristics

Arch Virol. 2013 Mar;158(3):521-9. doi: 10.1007/s00705-012-1514-5. Epub 2012 Oct 23.

Abstract

Dobrava-Belgrade virus (DOBV) is a human pathogen that has evolved in, and is hosted by, mice of several species of the genus Apodemus. We propose a subdivision of the species Dobrava-Belgrade virus into four related genotypes - Dobrava, Kurkino, Saaremaa, and Sochi - that show characteristic differences in their phylogeny, specific host reservoirs, geographical distribution, and pathogenicity for humans.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biological Evolution
  • Europe
  • Genotype
  • Hantavirus Infections / epidemiology
  • Hantavirus Infections / veterinary
  • Hantavirus Infections / virology*
  • Hemorrhagic Fever with Renal Syndrome / epidemiology*
  • Hemorrhagic Fever with Renal Syndrome / veterinary
  • Hemorrhagic Fever with Renal Syndrome / virology
  • Humans
  • Molecular Epidemiology
  • Murinae
  • Orthohantavirus / classification
  • Orthohantavirus / genetics*
  • Orthohantavirus / pathogenicity*
  • Phylogeny
  • Rodent Diseases / epidemiology
  • Rodent Diseases / virology
  • Species Specificity