Invasive aspergillosis: drug-dispensing systems as a source of filamentous fungal contamination in high-risk units?

P Gibert; E Brudieu; J F Timsit; L Foroni; A Thiébaut-Bertrand; B Allenet; H Pelloux; M-P Brenier Pinchart

doi:10.1016/j.jhin.2012.08.015

Invasive aspergillosis: drug-dispensing systems as a source of filamentous fungal contamination in high-risk units?

J Hosp Infect. 2012 Dec;82(4):293-6. doi: 10.1016/j.jhin.2012.08.015. Epub 2012 Oct 24.

Authors

P Gibert¹, E Brudieu, J F Timsit, L Foroni, A Thiébaut-Bertrand, B Allenet, H Pelloux, M-P Brenier Pinchart

Affiliation

¹ Pôle Pharmacie, Centre Hospitalier Universitaire de Grenoble, Grenoble, France. [email protected]

PMID: 23102819
DOI: 10.1016/j.jhin.2012.08.015

Abstract

High-risk units with air-control measures at Grenoble University Hospital are equipped with automated dispensing systems that are filled daily using drug trolleys routed from the pharmacy to the ward. The aim of this study was to evaluate the level of filamentous fungi (FF) contamination present in trolleys under usual conditions and after cleaning with Aniosurf(®) (fungicidal disinfectant). FF were detected in all samples, and 83.3% of samples were contaminated with Aspergillus fumigatus. Cleaning trolleys with Aniosurf(®) decreased the level of FF significantly, but contamination re-appeared within 24 h due to storage in a non-controlled environment.

MeSH terms

Aspergillus fumigatus / isolation & purification*
Cross Infection / prevention & control*
Disinfectants / administration & dosage*
Environmental Microbiology*
France
Hospitals, University
Humans
Infection Control / methods*
Invasive Pulmonary Aspergillosis / prevention & control*
Prospective Studies

Substances

Disinfectants