An emboligenic pulmonary abscess leading to ischemic stroke and secondary brain abscess

BMC Neurol. 2012 Nov 5:12:133. doi: 10.1186/1471-2377-12-133.

Abstract

Background: Ischemic stroke by septic embolism occurs primarily in the context of infective endocarditis or in patients with a right-to-left shunt and formation of a secondary cerebral abscess is a rare event. Erosion of pulmonary veins by a pulmonary abscess can lead to transcardiac septic embolism but to our knowledge no case of septic embolic ischemic stroke from a pulmonary abscess with secondary transformation into a brain abscess has been reported to date.

Case presentation: We report the case of a patient with a pulmonary abscess causing a septic embolic cerebral infarction which then transformed into a cerebral abscess. After antibiotic therapy and drainage of the abscess the patient could be rehabilitated and presented an impressive improvement of symptoms.

Conclusion: Septic embolism should be considered as cause of ischemic stroke in patients with pulmonary abscess and can be followed by formation of a secondary cerebral abscess. Early antibiotic treatment and repeated cranial CT-scans for detection of a secondary abscess should be performed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Brain Abscess / diagnosis
  • Brain Abscess / drug therapy
  • Brain Abscess / etiology*
  • Brain Ischemia / diagnosis*
  • Brain Ischemia / etiology
  • Brain Ischemia / prevention & control
  • Diagnosis, Differential
  • Fusobacteriaceae Infections / complications
  • Fusobacteriaceae Infections / diagnosis*
  • Fusobacteriaceae Infections / drug therapy
  • Humans
  • Lung Abscess / complications
  • Lung Abscess / diagnosis*
  • Lung Abscess / drug therapy
  • Male
  • Pulmonary Embolism / complications
  • Pulmonary Embolism / diagnosis*
  • Pulmonary Embolism / drug therapy
  • Stroke / diagnosis*
  • Stroke / etiology
  • Stroke / prevention & control
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents