Ototoxicity in dogs and cats

Vet Clin North Am Small Anim Pract. 2012 Nov;42(6):1259-71. doi: 10.1016/j.cvsm.2012.08.005. Epub 2012 Oct 10.

Abstract

A variety of drugs in veterinary use have side effects that can potentially damage the senses of hearing or balance in animals. A large body of literature exists on the incidence and mechanisms of ototoxicity in experimental animals and in humans, but little is documented in domestic dogs and cats. However, the generality of these adverse actions across species allows one to extrapolate and provide the veterinarian with insight into possible complications of chemotherapy.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Aminoglycosides / adverse effects
  • Aminoglycosides / therapeutic use
  • Animals
  • Anti-Bacterial Agents / adverse effects*
  • Anti-Bacterial Agents / therapeutic use
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use
  • Cat Diseases / chemically induced*
  • Cat Diseases / prevention & control
  • Cats
  • Cisplatin / adverse effects
  • Cisplatin / therapeutic use
  • Dog Diseases / chemically induced*
  • Dog Diseases / prevention & control
  • Dogs
  • Drug Therapy / veterinary*
  • Drug-Related Side Effects and Adverse Reactions
  • Hearing Disorders / chemically induced
  • Hearing Disorders / prevention & control
  • Hearing Disorders / veterinary*

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • Antineoplastic Agents
  • Cisplatin