Stem cell therapy for male infertility takes a step forward

Virginie Firlej; Virginie Barraud-Lange; Pierre Fouchet

doi:10.1016/j.stem.2012.10.006

Stem cell therapy for male infertility takes a step forward

Cell Stem Cell. 2012 Nov 2;11(5):585-6. doi: 10.1016/j.stem.2012.10.006.

Authors

Virginie Firlej¹, Virginie Barraud-Lange, Pierre Fouchet

Affiliation

¹ Institut National de la Santé et de la Recherche Médicale, Unité 1016, Institut Cochin, Paris, France.

PMID: 23122284
DOI: 10.1016/j.stem.2012.10.006

Abstract

The feasibility of using spermatogonial stem cells (SSCs) for cell-based infertility treatment has suffered from a lack of evidence in a preclinical nonhuman primate model. In this issue, Hermann et al. (2012) demonstrate that autologous and allogeneic transplantation of SSCs in testes of rhesus macaques produced functional sperm.

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MeSH terms

Animals
Male
Spermatogonia / transplantation*
Spermatozoa / physiology*
Testis / transplantation*