Outcomes after rectal cancer surgery in elderly nursing home residents

Dis Colon Rectum. 2012 Dec;55(12):1229-35. doi: 10.1097/DCR.0b013e318267bfe3.

Abstract

Background: As the population ages, an increasing number of elderly persons will undergo surgery for rectal cancer. The use of sphincter-sparing surgery in frail older adults is controversial.

Objective: The aim of this study was to examine mortality and bowel function after proctectomy in nursing home residents.

Design: This is a retrospective cohort study.

Setting: This investigation was conducted in nursing homes in the United States contracted with the Center for Medicare and Medicaid Services.

Patients: Nursing home residents age 65 and older undergoing proctectomy for rectal cancer (2000-2005) were included.

Main outcome measures: The primary outcomes measured were fecal incontinence and the 1-year mortality rate.

Results: Operative mortality was 18% after proctectomy with permanent colostomy and 13% after sphincter-sparing proctectomy (adjusted relative risk, 1.25 (95% CI 0.90-1.73), p = 0.188). One-year mortality was high: 40% after sphincter-sparing proctectomy and 51% after proctectomy with permanent colostomy (adjusted hazard ratio 1.32 (95% CI 1.09-1.60), p = 0.004). After sphincter-sparing proctectomy, 37% of residents were incontinent of feces. Residents with the poorest functional status (Minimum Data Set-Activities of Daily Living quartile 4) were significantly more likely to be incontinent of feces than residents with the best functional status (Minimum Data Set-Activities of Daily Living quartile 1) (76% vs 13%, adjusted relative risk 3.28 (95% CI 1.74- 6.18), p= 0.0002). Fecal incontinence was also associated with dementia (adjusted relative risk 1.55 (95% CI 1.15-2.09), p = 0.004) and renal failure (adjusted relative risk 1.93 (95% CI 1.10-3.38), p = 0.022).

Limitations: Measures of fecal incontinence in nursing home registries are not as well studied as those commonly used in clinical practice.

Conclusions: Sphincter-sparing proctectomy in nursing home residents is frequently associated with postoperative fecal incontinence and should be considered only for continent patients with good functional status.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Aged, 80 and over
  • Chi-Square Distribution
  • Fecal Incontinence / epidemiology*
  • Female
  • Humans
  • Male
  • Nursing Homes*
  • Poisson Distribution
  • Postoperative Complications / epidemiology*
  • Proportional Hazards Models
  • Rectal Neoplasms / mortality
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / surgery*
  • Retrospective Studies
  • Treatment Outcome
  • United States / epidemiology