Non-invasive high voltage electrical stimulation as a monitoring tool of nerve root function in lumbosacral surgery

Clin Neurophysiol. 2013 Apr;124(4):809-18. doi: 10.1016/j.clinph.2012.10.009. Epub 2012 Nov 8.

Abstract

Objective: To verify the safety and clinical use of non-invasive high-voltage electrical stimulation (HVES) in patients with compressive radiculopathy. To test the feasibility of HVES to survey nerve root function during lumbosacral surgery.

Methods: In 20 patients undergoing lumbosacral surgery for degenerative spinal diseases, compound muscle action potentials (CMAPs) evoked by maximal HVES were bilaterally recorded throughout surgery from L3 to S2 radicular territories. A preliminary study was performed in awake patients to rule out detrimental effects caused by HVES.

Results: Preoperative study confirmed the safety of HVES. Unexpectedly, a transient but significant remission of pain was observed after root stimulation. Intraoperative monitoring (IOM) was accomplished in all patients. HVES never hindered surgical procedures and never caused mechanical damage within the operatory field. In 4 patients acute, highly focal and reversible conduction failure was promptly detected by HVES in radicular territories congruent with the root manipulated at that moment.

Conclusions: HVES is a safe and sensitive tool to monitor nerve root function in lumbosacral surgery.

Significance: The method is based on the assumption that any acute conduction failure occurring during surgery can be immediately and unambiguously detected by HVES if root stimulation is supramaximal and delivered rostral to the surgical level.

MeSH terms

  • Action Potentials
  • Adult
  • Aged
  • Anesthesia
  • Electric Stimulation / methods*
  • Electrodes
  • Electromyography
  • Female
  • Humans
  • Low Back Pain / surgery
  • Lumbosacral Region / physiology*
  • Lumbosacral Region / surgery*
  • Male
  • Middle Aged
  • Monitoring, Intraoperative / methods*
  • Motor Neurons / physiology
  • Neuromuscular Junction / physiology
  • Neurosurgical Procedures / methods*
  • Pain Measurement
  • Preoperative Care
  • Radiculopathy / pathology
  • Radiculopathy / surgery
  • Software
  • Spinal Cord Compression / surgery
  • Spinal Nerve Roots / physiology*