Abstract
We report the case of a 66-year-old man with primary diffuse large B-cell lymphoma of the prostate presenting with urinary retention and dyschezia as first manifestation. Although a colostomy was needed due to rectal obstruction, rituximab-combined chemotherapy resulted in complete remission. He underwent stoma closure safely and has remained in complete remission for over 3years. Primary prostatic lymphoma is extremely rare, presenting as 0.1% of newly diagnosed lymphomas, but rituximab-containing chemotherapy seems to be as effective as for nodal lymphoma.
MeSH terms
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Aged
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Antibodies, Monoclonal, Murine-Derived / administration & dosage
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Antibodies, Monoclonal, Murine-Derived / therapeutic use*
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Combined Modality Therapy
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Constipation / etiology*
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Cyclophosphamide / therapeutic use
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Doxorubicin / therapeutic use
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Humans
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Lymphoma, Large B-Cell, Diffuse / complications
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Lymphoma, Large B-Cell, Diffuse / drug therapy*
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Lymphoma, Large B-Cell, Diffuse / pathology
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Lymphoma, Large B-Cell, Diffuse / surgery
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Male
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Prednisone / therapeutic use
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Prostate / pathology*
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Rectal Neoplasms / complications
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Rectal Neoplasms / drug therapy*
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Rectal Neoplasms / pathology
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Rectal Neoplasms / surgery
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Remission Induction
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Rituximab
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Urinary Retention / etiology*
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Vincristine / therapeutic use
Substances
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Antibodies, Monoclonal, Murine-Derived
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Rituximab
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisone