Clinical management of filovirus-infected patients

Viruses. 2012 Sep;4(9):1668-86. doi: 10.3390/v4091668. Epub 2012 Sep 21.

Abstract

Filovirus infection presents many unique challenges to patient management. Currently no approved treatments are available, and the recommendations for supportive care are not evidence based. The austere clinical settings in which patients often present and the sporadic and at times explosive nature of filovirus outbreaks have effectively limited the information available to evaluate potential management strategies. This review will summarize the management approaches used in filovirus outbreaks and provide recommendations for collecting the information necessary for evaluating and potentially improving patient outcomes in the future.

Keywords: Clinical management; Ebola; Filoviruses; Marburg; Outbreak; Treatment.

Publication types

  • Review

MeSH terms

  • Disease Outbreaks
  • Filoviridae / isolation & purification*
  • Filoviridae Infections / diagnosis*
  • Filoviridae Infections / epidemiology
  • Filoviridae Infections / pathology
  • Filoviridae Infections / therapy*
  • Humans
  • Treatment Outcome