Typing of nosocomial outbreaks of Acinetobacter baumannii by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry

J Clin Microbiol. 2013 Feb;51(2):603-6. doi: 10.1128/JCM.01811-12. Epub 2012 Nov 21.

Abstract

Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been evaluated for the identification of multidrug-resistant Acinetobacter baumannii nosocomial outbreaks in comparison with the repetitive sequence-based PCR DiversiLab system. The results suggest that MALDI-TOF MS can be used for real-time detection of Acinetobacter outbreaks before results from DNA-based systems are available.

MeSH terms

  • Acinetobacter Infections / diagnosis*
  • Acinetobacter Infections / epidemiology
  • Acinetobacter baumannii / classification*
  • Acinetobacter baumannii / isolation & purification
  • Bacterial Typing Techniques*
  • Cluster Analysis
  • Cross Infection / diagnosis*
  • Cross Infection / epidemiology
  • Disease Outbreaks
  • Humans
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization* / methods