Abstract
Few studies have correlated the results of interferon (gamma interferon) release assays (IGRAs) with known markers of tuberculosis (TB) treatment response. We report the results of serial QuantiFERON-TB gold in-tube assay (QFT) testing on 149 patients with active tuberculosis and correlate the results with smear and culture conversion. We show that QFT results do not offer much value for treatment monitoring of TB disease.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Antitubercular Agents / therapeutic use
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Biomarkers / metabolism
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Child
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Child, Preschool
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Female
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Humans
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Interferon-gamma / biosynthesis
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Interferon-gamma Release Tests*
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Male
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Middle Aged
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Mycobacterium tuberculosis* / immunology
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Sputum / microbiology
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Tuberculosis / diagnosis*
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Tuberculosis / drug therapy
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Young Adult
Substances
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Antitubercular Agents
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Biomarkers
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Interferon-gamma