Primary malignant melanoma of the esophagus with extensive intraepithelial extension

Kyoko Inadomi; Takatsugu Ishimoto; Masayuki Watanabe; Masaaki Iwatsuki; Kota Arima; Satoshi Ida; Yohei Nagai; Shiro Iwagami; Yoshifumi Baba; Yasuo Sakamoto; Yuji Miyamoto; Yumi Honda; Ken-ichi Iyama; Hideo Baba

doi:10.1016/j.athoracsur.2012.04.127

Primary malignant melanoma of the esophagus with extensive intraepithelial extension

Ann Thorac Surg. 2012 Dec;94(6):2105-7. doi: 10.1016/j.athoracsur.2012.04.127.

Authors

Kyoko Inadomi¹, Takatsugu Ishimoto, Masayuki Watanabe, Masaaki Iwatsuki, Kota Arima, Satoshi Ida, Yohei Nagai, Shiro Iwagami, Yoshifumi Baba, Yasuo Sakamoto, Yuji Miyamoto, Yumi Honda, Ken-ichi Iyama, Hideo Baba

Affiliation

¹ Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, and Department of Surgical Pathology, Kumamoto University Hospital, Kumamoto, Japan.

PMID: 23176922
DOI: 10.1016/j.athoracsur.2012.04.127

Abstract

Primary malignant melanoma of the esophagus (PMME) is an exceedingly rare tumor. The prognosis of PMME is very poor, and the 5-year survival rate is only 2.2% due to its aggressive biologic character. We present patient with PMME with wide extension into almost the entire esophagus, without endoscopic abnormalities. This patient's presentation is extremely valuable because it has enabled us to observe the long-term natural progression of PMME, including recurrent disease with a wide range of atypical melanocytic cells in the entire esophagus.

Publication types

Case Reports

MeSH terms

Diagnosis, Differential
Esophageal Neoplasms / pathology*
Esophageal Neoplasms / surgery
Esophagectomy / methods*
Esophagoscopy
Follow-Up Studies
Humans
Intestinal Mucosa / pathology*
Male
Melanoma / pathology*
Melanoma / surgery
Middle Aged
Neoplasm Invasiveness*