IgG myeloma presenting as a large mediastinal mass and pleural effusion

J Bronchology Interv Pulmonol. 2012 Jan;19(1):65-7. doi: 10.1097/LBR.0b013e31823fcc5b.

Abstract

Plasmacytoma, a rare form of plasma cell dyscrasia, refers to a neoplastic proliferation of plasma cells. Although the upper aerodigestive tract is the most common site for extramedullary plasmacytoma, mediastinal and pleural involvement is extremely rare. We report the case of a patient who presented with a large mediastinal mass and pleural effusion. Diagnosis was challenging and subsequently made as mediastinal extramedullary plasmacytoma with simultaneous myelomatous pleural effusion. Further investigations revealed multiple myeloma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy, Fine-Needle
  • Blood Protein Electrophoresis
  • Bronchoscopy
  • Chest Pain / diagnosis
  • Chest Pain / etiology
  • Diagnosis, Differential
  • Drainage
  • Endosonography*
  • Humans
  • Immunoglobulin G / metabolism
  • Male
  • Mediastinal Neoplasms / complications
  • Mediastinal Neoplasms / diagnosis*
  • Mediastinal Neoplasms / pathology
  • Mediastinoscopy
  • Multiple Myeloma / complications
  • Multiple Myeloma / diagnosis
  • Multiple Myeloma / pathology
  • Plasmacytoma / complications
  • Plasmacytoma / diagnosis*
  • Plasmacytoma / pathology
  • Pleural Effusion, Malignant / diagnosis*
  • Pleural Effusion, Malignant / etiology
  • Pleural Effusion, Malignant / pathology
  • Tomography, X-Ray Computed

Substances

  • Immunoglobulin G