Using singlet oxygen to synthesise the CDE-ring system of the pectenotoxins

Org Biomol Chem. 2013 Jan 28;11(4):537-41. doi: 10.1039/c2ob27158c. Epub 2012 Dec 4.

Abstract

A non-classical route to the key CDE-ring fragment of the pectenotoxins has been developed which showcases a remarkable singlet oxygen-mediated cascade reaction sequence to install the complete DE ring system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biological Products / chemical synthesis
  • Biological Products / chemistry
  • Chemistry Techniques, Synthetic
  • Macrolides / chemical synthesis*
  • Macrolides / chemistry*
  • Marine Toxins / chemical synthesis*
  • Marine Toxins / chemistry*
  • Singlet Oxygen / chemistry*

Substances

  • Biological Products
  • Macrolides
  • Marine Toxins
  • Singlet Oxygen