Dasatinib medication causing profound immunosuppression in a patient after haploidentical SCT: functional assays from whole blood as diagnostic clues

Bone Marrow Transplant. 2013 Jun;48(6):875-7. doi: 10.1038/bmt.2012.246. Epub 2012 Dec 10.

Authors

M Wölfl, F Langhammer, V Wiegering, M Eyrich, P G Schlegel

PMID: 23222377
DOI: 10.1038/bmt.2012.246

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Allografts
CD8-Positive T-Lymphocytes*
Child
DNA Virus Infections / blood
DNA Virus Infections / chemically induced
Dasatinib
Humans
Immunologic Deficiency Syndromes* / blood
Immunologic Deficiency Syndromes* / chemically induced
Lymphocyte Count
Lymphocytosis* / blood
Lymphocytosis* / chemically induced
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma / blood
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
Protein Kinase Inhibitors / administration & dosage
Protein Kinase Inhibitors / adverse effects*
Pyrimidines / administration & dosage
Pyrimidines / adverse effects*
Stem Cell Transplantation*
Thiazoles / administration & dosage
Thiazoles / adverse effects*

Substances

Protein Kinase Inhibitors
Pyrimidines
Thiazoles
Dasatinib