Elderly men and women benefit equally from prolonged resistance-type exercise training

J Gerontol A Biol Sci Med Sci. 2013 Jul;68(7):769-79. doi: 10.1093/gerona/gls241. Epub 2012 Dec 7.

Abstract

This study compares the effects of 6 months resistance-type exercise training (three times per week) between healthy elderly women (n = 24; 71±1 years) and men (n = 29; 70±1 years). Muscle mass (dual-energy x-ray absorptiometry-computed tomography), strength (one-repetition maximum), functional capacity (sit-to-stand time), muscle fiber characteristics (muscle biopsies), and metabolic profile (blood samples) were assessed. Leg lean mass (3% ± 1%) and quadriceps cross-sectional area (9% ± 1%) increased similarly in both groups. One-repetition maximum leg extension strength increased by 42% ± 3% (women) and 43% ± 3% (men). Following training, type II muscle fiber size had increased, and a type II muscle fiber specific increase in myonuclear and satellite cell content was observed with no differences between genders. Sit-to-stand time decreased similarly in both groups. Glycemic control and blood lipid profiles improved to a similar extent in both women and men. A generic resistance-type exercise training program can be applied for both women and men to effectively counteract the loss of muscle mass and strength with aging.

Keywords: Function; Men; Muscle mass; Sarcopenia; Strength; Women..

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorptiometry, Photon / methods
  • Aged
  • Aging*
  • Biomarkers
  • Body Composition
  • Cholesterol / blood
  • Cholesterol, HDL / blood
  • Dietary Supplements
  • Female
  • Glycated Hemoglobin / metabolism
  • Humans
  • Male
  • Muscle Fibers, Skeletal / metabolism*
  • Muscle Strength*
  • Muscle, Skeletal / metabolism
  • Resistance Training*
  • Sarcopenia / diagnostic imaging
  • Sarcopenia / prevention & control*

Substances

  • Biomarkers
  • Cholesterol, HDL
  • Glycated Hemoglobin A
  • Cholesterol