A case of central nervous system lymphoma manifesting as multiple patchy white matter lesions with a past history of tonsil lymphoma

Kurume Med J. 2012;59(1-2):33-8. doi: 10.2739/kurumemedj.59.33.

Abstract

Lymphoma of the central nervous system (CNS) parenchyma is known to present as a well-demarcated mass with strong and homogenous gadolinium enhancement in the periventricular and/or superficial region. We report a case of central nervous system lymphoma (CNSL) manifesting as multiple white matter lesions with non-tumorous patchy or ring-like enhancement and partial spontaneous resolution on magnetic resonance imaging (MRI). Such findings are unusual and could lead to misdiagnosis without pathological evaluation.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Central Nervous System Neoplasms / drug therapy
  • Central Nervous System Neoplasms / pathology*
  • Cyclophosphamide / administration & dosage
  • Doxorubicin / administration & dosage
  • Humans
  • Lymphoma / drug therapy
  • Lymphoma / pathology*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Prednisone / administration & dosage
  • Tonsillar Neoplasms / drug therapy
  • Tonsillar Neoplasms / pathology*
  • Vincristine / administration & dosage

Substances

  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone

Supplementary concepts

  • CHOP protocol