Abstract
Macrolide resistance rates of Mycoplasma pneumoniae in the Beijing population were as high as 68.9%, 90.0%, 98.4%, 95.4%, and 97.0% in the years 2008 to 2012, respectively. Common macrolide-resistant mobile genetic elements were not detected with any isolate. These macrolide-resistant isolates came from multiple clones rather than the same clone. No massive aggregation of a particular clone was found in a specific period.
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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China
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Clone Cells
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Drug Resistance, Bacterial / drug effects*
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Drug Resistance, Bacterial / genetics
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Humans
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Macrolides / pharmacology*
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Microbial Sensitivity Tests
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Minisatellite Repeats
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Mutation
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Mycoplasma pneumoniae / drug effects*
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Mycoplasma pneumoniae / genetics*
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Mycoplasma pneumoniae / isolation & purification
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Pneumonia, Mycoplasma / drug therapy*
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Pneumonia, Mycoplasma / microbiology
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Public Health Surveillance
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RNA, Ribosomal, 23S / genetics*
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Sequence Analysis, DNA
Substances
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Anti-Bacterial Agents
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Macrolides
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RNA, Ribosomal, 23S