Characteristics, treatment, and outcomes of periprocedural cerebrovascular accidents during electrophysiologic procedures

J Interv Card Electrophysiol. 2013 Jun;37(1):41-6. doi: 10.1007/s10840-012-9766-2. Epub 2012 Dec 22.

Abstract

Objectives: We sought to identify the characteristics, treatment, and outcomes of periprocedural cerebrovascular accident (PCVA) during electrophysiologic (EP) procedures.

Background: Periprocedural cerebrovascular accident is one of the most feared complications during EP procedures with very few data regarding its characteristics, management, and outcomes.

Methods: Between January 1998 and December 2008, we reviewed 30,032 invasive EP procedures for PCVA occurrence and characteristics. Management and outcomes were also determined.

Results: Thirty-eight CVAs were identified. Twenty (53 %) were intraprocedural and 18 (47 %) postprocedural. Thirty-two (84 %) were classified as strokes and six (16 %) as transient ischemic attacks. All CVAs except one (37, 97 %) were ischemic and the vast majority occurred during ablation procedures (36, 95 %). Among the 31 patients with ischemic stroke, 11 (35 %) were treated with reperfusion (eight catheter-based therapy and three intravenous t-PA) of whom five (46 %) had complete recovery, three (27 %) had partial recovery, and three (27 %) had no recovery. No hemorrhagic transformations occurred.

Conclusion: Periprocedural cerebrovascular accident during EP procedures is rare and is almost always ischemic. It occurs more frequently during ablation procedures. Reperfusion therapy is feasible and safe.

MeSH terms

  • Aged
  • Cardiac Catheterization / mortality*
  • Electrophysiologic Techniques, Cardiac / mortality*
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Ohio / epidemiology
  • Retrospective Studies
  • Risk Assessment
  • Stroke / mortality*
  • Stroke / therapy*
  • Survival Analysis
  • Survival Rate
  • Treatment Outcome