Prolonged fever and splinter hemorrhages in an immunocompetent traveler with disseminated histoplasmosis

J Travel Med. 2013 Jan-Feb;20(1):57-9. doi: 10.1111/jtm.12000.

Abstract

We present a case of progressive disseminated histoplasmosis in an immunocompetent traveler. Histoplasmosis was acquired in South America; its manifestations included prolonged fever, splinter hemorrhages, erythema multiforme, arthritis, and mediastinal lymphadenopathy. To the best of our knowledge no splinter hemorrhages had previously been reported in a patient with histoplasmosis.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Antifungal Agents / administration & dosage
  • Arthritis / etiology
  • Biopsy
  • DNA, Fungal*
  • Fever / etiology
  • Genes, Fungal*
  • Hemorrhage / etiology
  • Histoplasma* / drug effects
  • Histoplasma* / genetics
  • Histoplasma* / isolation & purification
  • Histoplasma* / pathogenicity
  • Histoplasmosis* / complications
  • Histoplasmosis* / drug therapy
  • Histoplasmosis* / epidemiology
  • Histoplasmosis* / microbiology
  • Histoplasmosis* / pathology
  • Histoplasmosis* / physiopathology
  • Humans
  • Itraconazole / administration & dosage*
  • Lymphatic Diseases / pathology
  • Male
  • Middle Aged
  • Multiple Pulmonary Nodules / etiology
  • Sequence Analysis, DNA / methods*
  • Serologic Tests / methods
  • Travel
  • Treatment Outcome
  • Weight Loss

Substances

  • Antifungal Agents
  • DNA, Fungal
  • Itraconazole