A hierarchical scheme for geodesic anatomical labeling of airway trees

Med Image Comput Comput Assist Interv. 2012;15(Pt 3):147-55. doi: 10.1007/978-3-642-33454-2_19.

Abstract

We present a fast and robust supervised algorithm for labeling anatomical airway trees, based on geodesic distances in a geometric tree-space. Possible branch label configurations for a given tree are evaluated based on distances to a training set of labeled trees. In tree-space, the tree topology and geometry change continuously, giving a natural way to automatically handle anatomical differences and noise. The algorithm is made efficient using a hierarchical approach, in which labels are assigned from the top down. We only use features of the airway centerline tree, which are relatively unaffected by pathology. A thorough leave-one-patient-out evaluation of the algorithm is made on 40 segmented airway trees from 20 subjects labeled by 2 medical experts. We evaluate accuracy, reproducibility and robustness in patients with chronic obstructive pulmonary disease (COPD). Performance is statistically similar to the inter- and intra-expert agreement, and we found no significant correlation between COPD stage and labeling accuracy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Bronchography / methods*
  • Humans
  • Pattern Recognition, Automated / methods*
  • Pulmonary Disease, Chronic Obstructive / diagnostic imaging*
  • Radiographic Image Enhancement / methods
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Subtraction Technique*
  • Tomography, X-Ray Computed / methods*