HER2-directed T-cell receptor-mimicking antibody: a "Me Too" or an example of novel antitumor aggressive mimicry?

MeSH terms

• Animals
• Antibodies, Monoclonal / pharmacology*
• Antibodies, Monoclonal, Humanized / pharmacology*
• Antineoplastic Agents / pharmacology*
• Apoptosis / drug effects*
• Female
• HLA-A2 Antigen / drug effects*
• Humans
• Intracellular Signaling Peptides and Proteins / drug effects*
• Neoplasms / drug therapy*
• Oncogene Proteins, Fusion / antagonists & inhibitors*
• Receptor, ErbB-2 / antagonists & inhibitors*
• Receptors, Antigen, T-Cell / agonists*
• Trastuzumab