Abstract
We demonstrated that visfatin expressed in monocytes and neutrophils and increased their reactivity in male acute ST-segment elevation myocardial infarction patients. Furthermore, visfatin was strongly appeared in lipid rich coronary rupture plaques and macrophages. These results suggest another explanation about leukocytes mediated visfatin that may play a pathogenesis role in coronary vulnerable plaques rupture.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acute Disease
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Aged
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Humans
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Immunohistochemistry
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Macrophages / metabolism*
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Male
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Middle Aged
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Monocytes / metabolism*
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Myocardial Infarction / etiology
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Myocardial Infarction / metabolism*
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Nicotinamide Phosphoribosyltransferase / analysis
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Nicotinamide Phosphoribosyltransferase / genetics
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Nicotinamide Phosphoribosyltransferase / physiology*
Substances
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Nicotinamide Phosphoribosyltransferase