Infectious chest complications in haematological malignancies

Diagn Interv Imaging. 2013 Feb;94(2):193-201. doi: 10.1016/j.diii.2012.12.002. Epub 2013 Jan 10.

Abstract

The management of infections in haematology is dictated by the patient's type of acquired or induced immune deficiency (neutropenia, deficiency in cell-mediated or antibody-mediated immunity), and findings from clinical examination, laboratory studies, or morphologic investigations. The CT scan dominates in the initial management and follow-up of these patients, since clinical features very often appear to be non-specific. The radiologist's role is to guide the clinician towards a specific diagnosis such as aspergillosis or pneumocystosis, or to point them towards a non-infectious cause: tumour localisation, hypervolaemia, bronchiolitis obliterans suggestive of GVH disease, drug toxicity, or embolism.

MeSH terms

  • Adult
  • Aged
  • Algorithms
  • Aspergillosis / diagnosis
  • Aspergillosis / diagnostic imaging
  • Bronchiolitis Obliterans / diagnosis
  • Embolism / diagnosis
  • Female
  • France
  • Hematologic Neoplasms / complications*
  • Hematologic Neoplasms / diagnosis
  • Hematologic Neoplasms / pathology
  • Humans
  • Immunologic Deficiency Syndromes / diagnosis
  • Immunologic Deficiency Syndromes / immunology
  • Immunologic Deficiency Syndromes / therapy
  • Infections / diagnostic imaging*
  • Lung Diseases / chemically induced
  • Lung Diseases / diagnosis
  • Lung Diseases / etiology
  • Male
  • Middle Aged
  • Neoplasms / diagnosis
  • Pneumonia, Pneumocystis / diagnosis
  • Pneumonia, Pneumocystis / diagnostic imaging
  • Thorax* / microbiology
  • Thorax* / pathology
  • Tomography, X-Ray Computed*

Supplementary concepts

  • Immune Deficiency Disease