Intracranial aneurysm and recessive polycystic kidney disease: the third reported case

JAMA Neurol. 2013 Jan;70(1):114-6. doi: 10.1001/jamaneurol.2013.584.

Abstract

Objective: To highlight the possible association of intracranial aneurysm with autosomal recessive polycystic kidney disease.

Design, setting, and patient: To our knowledge, this association has been reported only twice in the medical literature. We herein report the case of a 21-year-old man with autosomal recessive polycystic kidney disease, presenting with subarachnoid hemorrhage secondary to a ruptured intracranial aneurysm, at our institution.

Results: In the presence of only 3 cases in the medical literature, one might conclude they are a simple coincidence. However, should this association exist, such as with the dominant form, then the neurologic prognosis and even the life of young patients may be at stake.

Conclusions: Given the devastating consequences of intracranial bleeding in young patients, early neurologic screening may be warranted.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Comorbidity
  • Humans
  • Intracranial Aneurysm / complications*
  • Magnetic Resonance Angiography
  • Male
  • Polycystic Kidney, Autosomal Recessive / epidemiology*
  • Subarachnoid Hemorrhage / epidemiology*
  • Subarachnoid Hemorrhage / etiology
  • Young Adult