First night effect analysis in a cohort of young children with autism spectrum disorder

J Clin Sleep Med. 2013 Jan 15;9(1):67-70. doi: 10.5664/jcsm.2344.

Abstract

Study objectives: To evaluate for the first night effect (FNE) in a group of young children with autism.

Design: Analysis of polysomnographic data from a 2-night sleep laboratory study.

Setting: Clinical Center of the National Institutes of Health.

Patients or participants: 15 children (aged 2-10 years) with a diagnosis of an ASD.

Interventions: None.

Measurements and results: Polysomnographic analysis showed the presence of a FNE for wake after sleep onset minutes, stage 2, and sleep efficiency, but not for REM sleep parameters or TST.

Conclusions: In this 2-night polysomnographic analysis of sleep stages in young children with autism, we did not find the expected second night increase in total sleep time or REM sleep percentage or a decrease in REM sleep latency. This lack of an FNE for TST and REM parameters suggests that a single-night polysomnogram may be sufficient to evaluate children with an ASD for TST or REM parameters.

MeSH terms

  • Child
  • Child Development Disorders, Pervasive / complications*
  • Child Development Disorders, Pervasive / physiopathology
  • Child Development Disorders, Pervasive / psychology
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Polysomnography* / methods
  • Polysomnography* / psychology
  • Sleep / physiology
  • Sleep Stages / physiology
  • Sleep Wake Disorders / complications*
  • Sleep Wake Disorders / diagnosis
  • Sleep Wake Disorders / physiopathology
  • Time Factors