Recognition, diagnosis and referral of patients with Dupuytren's disease: a review of current concepts for general practitioners in Europe

Curr Med Res Opin. 2013 Mar;29(3):269-77. doi: 10.1185/03007995.2013.766163. Epub 2013 Jan 29.

Abstract

Background: Dupuytren's disease (DD) is a fairly prevalent yet under-recognised disorder of the palmar fascia, resulting in fixed-flexion contractures of joints in the hand. Numerous population-based studies have been conducted in countries around the world, and published prevalence estimates vary widely. Nevertheless, most studies have shown that the prevalence of DD increases with age. Because the global population is aging, the prevalence of DD will also continue to increase.

Scope: Patients with DD typically present to a variety of physicians, generalists and specialists alike. Thus, it is critical that providers have clear guidance on the early recognition of signs and symptoms, comprehensive evaluation of potential risk factors, differential diagnosis and when to refer a patient for treatment. Treatment options range from minimally invasive injections with collagenase to surgery.

Findings: Results from a large-scale study of the surgical management of DD in Europe indicate that most DD diagnoses and referrals are made by general practitioners, but there is much inter-country variation. Different patient- and physician-based factors affect diagnosis rates and referral pathways. Different healthcare systems and regulations are also influential. A simple management algorithm is provided herein and explained.

Conclusion: It is important for generalists to understand the natural history of DD and the potential benefits of early referral and treatment. General practitioners should diagnose and/or refer patients with DD to a specialist as early as possible to optimise disease management and treatment outcomes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Collagenases / therapeutic use*
  • Dupuytren Contracture* / diagnosis
  • Dupuytren Contracture* / drug therapy
  • Dupuytren Contracture* / radiotherapy
  • Dupuytren Contracture* / surgery
  • Europe
  • Finger Joint / pathology*
  • Humans
  • Prevalence
  • Treatment Outcome

Substances

  • Collagenases