Abstract
While studies have examined psychosocial stress in non-clinical psychosis (NCP), it is unclear if the elevated cortisol seen in schizophrenia also occurs in this group. Cortisol was sampled in High- and Low-NCP groups, and findings of elevated resting cortisol in the former suggest that hypothalamic-pituitary-adrenal-axis dysfunction underlies a psychosis continuum.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Adolescent
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Female
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Humans
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Hydrocortisone / metabolism*
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Hypothalamo-Hypophyseal System / metabolism
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Hypothalamo-Hypophyseal System / physiopathology*
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Male
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Pituitary-Adrenal System / metabolism
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Pituitary-Adrenal System / physiopathology*
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Psychotic Disorders / metabolism
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Psychotic Disorders / physiopathology*
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Stress, Psychological / metabolism
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Stress, Psychological / physiopathology
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Young Adult