A fluorescent ratiometric chemodosimeter for Cu2+ based on TBET and its application in living cells

Org Lett. 2013 Feb 1;15(3):492-5. doi: 10.1021/ol3032889. Epub 2013 Jan 22.

Abstract

Based on a through bond energy transfer (TBET) between Rhodamine and a naphthalimide fluorophore, a fluorescent ratiometric chemodosimeter RN1 was designed and prepared for single selective detection of Cu(2+) in aqueous solution and in living cells, as Cu(2+) acts as not only a selective recognizing guest but also a hydrolytic promoter.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Copper / analysis*
  • Female
  • Fluorescent Dyes / chemical synthesis*
  • Fluorescent Dyes / chemistry
  • Humans
  • Hydrolysis
  • Molecular Structure
  • Naphthalimides / chemistry*
  • Rhodamines / chemistry*
  • Spectrometry, Fluorescence

Substances

  • Fluorescent Dyes
  • Naphthalimides
  • Rhodamines
  • Copper