[Stability of PEGylated puerarin under different storage conditions]

Zhongguo Zhong Yao Za Zhi. 2012 Nov;37(22):3391-4.
[Article in Chinese]

Abstract

Objective: To detect the stability of PEGylated puerarin (PEG-PUE), in order to provide experimental basis for storage conditions of PEGylated puerarin.

Method: First, a method for determining the content of PEG-PUE was established. Next, a system study was conducted for the stability of PEG-PUE affected by different factors such as temperature, humidity, light and light avoidance.

Result: PEG-PUE was severely degraded under the conditions of high temperature, high humidity and light. It was also seriously degraded under high temperature.

Conclusion: PEG-PUE shall be stored under low temperature and in a dark and dry environment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Stability
  • Drug Storage*
  • Isoflavones / chemistry*
  • Light
  • Polyethylene Glycols / chemistry*
  • Temperature

Substances

  • Isoflavones
  • Polyethylene Glycols
  • puerarin