A 10-year (1999 ~ 2008) retrospective multi-center study of breast cancer surgical management in various geographic areas of China

Breast. 2013 Oct;22(5):676-81. doi: 10.1016/j.breast.2013.01.004. Epub 2013 Feb 4.

Abstract

Purpose: To study the change of surgical treatments for breast cancer in China over the recent 10 years and the relationship between such a changes and social economical development.

Methods: The data were extracted from the 10-year database of female primary breast cancer at 7 tertiary hospitals from various geographic areas in China. The Chi-square Cochran-Armitage trend test was used to measure the difference.

Results: Over the 10 year period, mastectomy showed a decline trend while breast conserving surgeries increased. The modified radical mastectomy was the primarily surgical treatment. Among various types of mastectomies, modified radical mastectomy was increasing while Halsted radical mastectomy had shown a decrease trend; no significant changes were observed for the simple mastectomy. Halsted radical mastectomy and breast conserving surgery were used in a higher proportion in high economic areas than low economic areas, while the modified radical mastectomy has been underused in hospitals from high economic areas.

Conclusions: Modified radical mastectomy was the overall most common choice of operation in China. Breast conserving surgery has been less popular but had been showing an increasing trend. Halsted radical mastectomy has still been in use but showing a decrease these years. Surgeries were not adherent to guidelines completely and needed further effective training.

Keywords: AJCC; American Joint Committee on Cancer; BC; BCS; BMI; Breast conserving surgery; Change of surgical managements of breast cancer; GDP; Halsted radical mastectomy; MRI; Modified radical mastectomy; body mass index; breast cancer; breast conserving surgery; gross domestic product; magnetic resonance imaging.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / surgery*
  • China
  • Economic Development / trends*
  • Female
  • Humans
  • Mastectomy / trends*
  • Mastectomy, Modified Radical / trends
  • Mastectomy, Segmental / trends
  • Mastectomy, Simple / trends
  • Middle Aged
  • Organ Sparing Treatments / trends*
  • Retrospective Studies
  • Socioeconomic Factors
  • Tertiary Care Centers / trends
  • Young Adult