In 2000-2009 in Lazio Region (Italy), 3% of reported occupational diseases occurred among foreign workers. Compared with foreigners, Italian workers more frequently reported Neoplasia (2.2% vs. 0.9%), Asbestosis (1.9% vs. 0.2%), Silicosis (1.5% vs. 0.2), while Skin Diseases were less frequently reported (1.2 vs. 2.5). Compared with foreigners, Italian workers reported more frequently occupational diseases in division "Transport" (11.1% vs. 4.6%), "Energy-Water" (6.4% vs. 1.8%), "Health System" (3.3% vs. 2.3%), "Chemical Industry" (2.0% vs. 0.2%). Compared with foreigners, Italian more frequently were acknowledged as affected by an occupational disease (27.6% vs. 14.6%). All these finding were substantially expected.