The Authors analyse the Italian, technical series called Manuali Hoepli, devoted to promote technical knowledge in the second half of XIXth century. Johann Ulrich (Ulrico) Hoepli (1847-1935) came from Switzerland to Milan in 1870, and translated into Italian some volumes edited by Macmillan in London (from Science Primers series). During his life, he printed 2000 Manuali Hoepli. Some of them were devoted to Occupational Medicine. Five volumes are presented: Magrini's one was devoted to technical devices to prevent industrial accidents; Allevi's Manual was printed when Milan Clinica del Lavoro was preparing; Altarelli and Bortolotto's manuals show us the fascist way of social medicine.