The 14th Biennial Meeting of the International Gynecologic Cancer Society (IGCS 2012) was held in Vancouver, BC, Canada last October 12–16, 2012 and focused on “Uniting the Globe in the fight against gynecologic cancers”. Two thousand cancer specialists with an interest in gynecologic cancers gathered to discuss the latest innovations in research, clinical practice and technology. There were 65 oral presentations, 78 brief communications and 826 poster presentations. These were focused on ovarian, endometrial, cervical and vulvo-vaginal and breast cancer. This report highlights some of the phase 2 and 3 clinical trials in gynecological malignancies and other selected studies.