Prevalence of extended-spectrum β-lactamase-producing Enterobacteriaceae in humans living in municipalities with high and low broiler density

Clin Microbiol Infect. 2013 Jun;19(6):E256-9. doi: 10.1111/1469-0691.12150. Epub 2013 Feb 11.

Abstract

Prevalence of, and risk factors for, carriage of extended-spectrum β-lactamase (ESBL) -producing Enterobacteriaceae were determined for 1025 Dutch adults in municipalities with either high or low broiler densities. Overall prevalence of ESBL carriage was 5.1%. The hypothesis that individuals in areas with high broiler densities are at greater risk for ESBL carriage was rejected, as the risk was lower (OR = 0.45; p 0.009) for these individuals. Owning a horse increased the risk (OR = 4.69; p ≤0.0001), but horse owners often owned multiple species of companion animals. Routes of transmission from animals to humans in the community, and the role of poultry in this process, remain to be elucidated.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Chickens*
  • Cities*
  • Enterobacteriaceae / metabolism*
  • Enterobacteriaceae Infections / epidemiology*
  • Enterobacteriaceae Infections / microbiology
  • Enterobacteriaceae Infections / transmission
  • Female
  • Humans
  • Male
  • Middle Aged
  • Netherlands / epidemiology
  • Population Density
  • Prevalence
  • Risk Factors
  • Young Adult
  • beta-Lactamases / biosynthesis*

Substances

  • beta-Lactamases