BCR-ABL1 is a secondary event after JAK2V617F in patients with polycythemia vera who develop chronic myeloid leukemia

Blood. 2013 Feb 14;121(7):1238-9. doi: 10.1182/blood-2012-11-467787.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Amino Acid Substitution
  • Colony-Forming Units Assay
  • Disease Progression
  • Genes, abl*
  • Hematopoietic Stem Cells / pathology
  • Homozygote
  • Humans
  • Janus Kinase 2 / genetics*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / enzymology
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / etiology*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
  • Mutation, Missense
  • Polycythemia Vera / complications*
  • Polycythemia Vera / enzymology
  • Polycythemia Vera / genetics*
  • Polycythemia Vera / pathology

Substances

  • JAK2 protein, human
  • Janus Kinase 2