Abstract
Tumor-to-tumor metastasis is a fairly rare phenomenon. The lung cancers are the most common donors, but are exceedingly rare as recipients. Here we report a case of a lung adenocarcinoma acting as the recipient of papillary thyroid carcinoma, with multiple spreading foci of the two cancers in the lung simultaneously. The morphology and immunohistochemistry (Napsin-A, Thyroglobulin) are very important in differential diagnosis of lung primary adenocarcinoma and metastatic papillary thyroid carcinoma.
Virtual slides:
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Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenocarcinoma / chemistry
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Adenocarcinoma / pathology*
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Adenocarcinoma / surgery
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Adenocarcinoma of Lung
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Aged
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Aspartic Acid Endopeptidases / analysis
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Biomarkers, Tumor / analysis
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Carcinoma / chemistry
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Carcinoma / secondary*
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Carcinoma / surgery
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Carcinoma, Papillary
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Diagnosis, Differential
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Humans
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Immunohistochemistry
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Lung Neoplasms / chemistry
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Lung Neoplasms / pathology*
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Lung Neoplasms / surgery
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Male
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Multimodal Imaging
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Positron-Emission Tomography
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Predictive Value of Tests
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Thyroglobulin / analysis
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Thyroid Cancer, Papillary
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Thyroid Neoplasms / chemistry
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Thyroid Neoplasms / pathology*
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Thyroid Neoplasms / surgery
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Tomography, X-Ray Computed
Substances
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Biomarkers, Tumor
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Thyroglobulin
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Aspartic Acid Endopeptidases
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NAPSA protein, human