Abstract
A new alkaloid was isolated from the ethyl acetate extract of the culture of a termite-associated Streptomyces koyangensis BY-4. The structure of 1 was elucidated by using MS, NMR, electronic circular dichroism data, and computational approaches. Compound 1 showed weak antimicrobial activities against a panel of test microbes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemistry
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Alkaloids / isolation & purification*
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Alkaloids / pharmacology
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Animals
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Aspergillus niger / drug effects
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Bacillus subtilis / drug effects
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Candida albicans / drug effects
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Circular Dichroism
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Cryptococcus neoformans / drug effects
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Escherichia coli / drug effects
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Indolizines / chemistry
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Indolizines / isolation & purification*
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Indolizines / pharmacology
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Isoptera / microbiology*
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Microbial Sensitivity Tests
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Micrococcus luteus / drug effects
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Pseudomonas aeruginosa / drug effects
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Staphylococcus aureus / drug effects
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Streptococcus pyogenes / drug effects
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Streptomyces / chemistry*
Substances
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2-ethyl-7-hydroxy-6,7-dihydro-5H-indolizin-3-one
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Alkaloids
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Indolizines