Three-dimensional rotational X-ray acquisition technique is reducing patients' cancer risk in coronary angiography

Catheter Cardiovasc Interv. 2013 Oct 1;82(4):E419-27. doi: 10.1002/ccd.24879. Epub 2013 Jul 1.

Abstract

Objectives: The purpose of this study was to assess patient-specific organ doses and cancer risk with 3D-rotational acquisitions versus the current standard of multiple single-plane coronary angiography (CA).

Background: Catheter-based CA remains one of the most commonly performed diagnostic invasive procedures delivering a relatively high radiation dose to the patient. With the introduction of flat-panel technology, three-dimensional rotational angiography became an alternative for the conventional two-dimensional angiography. However, limited information is available on the difference in patient radiation exposure with both acquisition techniques.

Methods: Eighty adult patients (45 males, age 38-93 years) were randomly assigned to the rotational or standard angiography group. Exposure parameters were registered and skin dose distribution was measured during the procedure. Patient-specific organ doses and related cancer risks were assessed with dedicated software.

Results: Rotational angiograms were associated with 33% lower KAP-values (decrease from 49.99 Gycm(2) to 33.37 Gycm(2), P < 0.001). A significant (P < 0.001) lower peak skin dose was measured with rotational acquisitions (80 mGy, median) versus planar imaging (172 mGy, median). Moreover, the skin dose was smoothed over the whole chest of the patient. Contrast medium consumption decreased from 104 mL to 73 mL (P < 0.001) with the use of 3D-imaging. The reduction in radiation exposure resulted in a corresponding decrease of organ doses. The latter contributed to an overall cancer risk reduction of 21% for males and 50% for females.

Conclusions: The current study demonstrates that in CA radiation risk reduction is feasible by using a rotational acquisition technique.

Keywords: radiation dose; radiation risk; rotational angiography.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Belgium
  • Cineangiography / adverse effects
  • Cineangiography / methods*
  • Contrast Media
  • Coronary Angiography / adverse effects
  • Coronary Angiography / methods*
  • Coronary Vessels / diagnostic imaging*
  • Female
  • Humans
  • Imaging, Three-Dimensional*
  • Male
  • Middle Aged
  • Neoplasms, Radiation-Induced / etiology
  • Neoplasms, Radiation-Induced / prevention & control
  • Patient Safety
  • Predictive Value of Tests
  • Radiation Dosage*
  • Radiation Monitoring / methods
  • Radiographic Image Interpretation, Computer-Assisted*
  • Risk Assessment
  • Risk Factors
  • Skin / radiation effects

Substances

  • Contrast Media