Peripheral blood stem cell transplantation in a significant body weight difference between a smaller donor and a larger recipient: a case report

Michinori Funato; Hideo Kaneko; Hideo Sasai; Kazuo Kubota; Michio Ozeki; Kaori Kanda; Zenichiro Kato; Naomi Kondo

doi:10.1016/j.transci.2013.01.015

Peripheral blood stem cell transplantation in a significant body weight difference between a smaller donor and a larger recipient: a case report

Transfus Apher Sci. 2013 Dec;49(3):504-6. doi: 10.1016/j.transci.2013.01.015. Epub 2013 Feb 16.

Authors

Michinori Funato¹, Hideo Kaneko, Hideo Sasai, Kazuo Kubota, Michio Ozeki, Kaori Kanda, Zenichiro Kato, Naomi Kondo

Affiliation

¹ Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan. Electronic address: [email protected].

PMID: 23422651
DOI: 10.1016/j.transci.2013.01.015

Abstract

Allogeneic peripheral blood stem cell transplantation (PBSCT) is becoming a common transplantation procedure in children. However, few benefits have been reported, in particular in regard to the choice of small children as donors for larger recipients. We report a case of relapsed acute myeloid leukemia (body weight 52 kg and blood type O) who underwent allogeneic PBSCT from his smaller human leukocyte antigen-matched brother (body weight 29.9 kg and blood type A).

Keywords: Benefits of younger donors; Peripheral blood stem cell collection; Peripheral blood stem cell transplantation; Safety of donors; Significant body weight difference.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Body Weight / physiology*
Child
Humans
Leukemia, Myeloid, Acute / surgery*
Male
Peripheral Blood Stem Cell Transplantation / adverse effects
Peripheral Blood Stem Cell Transplantation / methods*
Tissue Donors
Transplantation, Homologous