Homing frequency of human T cells inferred from peripheral blood depletion kinetics after sphingosine-1-phosphate receptor blockade

J Allergy Clin Immunol. 2013 May;131(5):1440-3.e7. doi: 10.1016/j.jaci.2012.12.1520. Epub 2013 Feb 21.

Authors

Matthias Mehling, Volker Brinkmann, Anne-Valerie Burgener, Patrick Gubser, Andrew D Luster, Ludwig Kappos, Christoph Hess

PMID: 23434284
DOI: 10.1016/j.jaci.2012.12.1520

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Case-Control Studies
Chemotaxis / drug effects
Chemotaxis / immunology*
Fingolimod Hydrochloride
Humans
Immunosuppressive Agents / pharmacology
Lymphocyte Depletion*
Multiple Sclerosis, Relapsing-Remitting / drug therapy
Multiple Sclerosis, Relapsing-Remitting / immunology
Multiple Sclerosis, Relapsing-Remitting / pathology
Propylene Glycols / pharmacology
Receptors, Lysosphingolipid / antagonists & inhibitors*
Sphingosine / analogs & derivatives
Sphingosine / pharmacology
T-Lymphocyte Subsets / drug effects
T-Lymphocyte Subsets / immunology*

Substances

Immunosuppressive Agents
Propylene Glycols
Receptors, Lysosphingolipid
Fingolimod Hydrochloride
Sphingosine